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1-amino-5-chloropentan-2-ol

  • Name 1-amino-5-chloropentan-2-ol
  • CAS 94157-97-8
  • Purity 99%
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Product Details

Export Top Purity 1-amino-5-chloropentan-2-ol 94157-97-8 In Stock

  • Molecular Formula: C5H12ClNO
  • Molecular Weight: 137.609
  • Vapor Pressure: 0.00156mmHg at 25°C 
  • Boiling Point: 262.3°Cat760mmHg 
  • Flash Point: 112.4°C 
  • PSA: 46.25000 
  • Density: 1.109g/cm3 
  • LogP: 1.02530 

1-amino-5-chloropentan-2-ol(Cas 94157-97-8) Usage

Derivative

Pentanol

Chlorine atom

Attached to the fifth carbon

Amino group

Attached to the first carbon

Physical state

Colorless liquid

Odor

Slightly sweet

Primary use

Intermediate in the synthesis of pharmaceuticals and other organic compounds

Presence of amino and hydroxyl groups

Useful in the production of various pharmacological agents

Reagent

Used in organic chemistry reactions

Classification

Hazardous substance

Handling

Requires proper care and precautions

General Description

1-amino-5-chloropentan-2-ol is a chemical compound with the molecular formula C5H12NOCl. It is a derivative of pentanol, with a chlorine atom attached to the fifth carbon and an amino group attached to the first carbon. The compound is a colorless liquid with a slightly sweet odor. It is primarily used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. The presence of both an amino and a hydroxyl group in its structure makes it useful in the production of various pharmacological agents. It is also used as a reagent in organic chemistry reactions. 1-amino-5-chloropentan-2-ol is classified as a hazardous substance and should be handled with proper care and precautions.

InChI:InChI=1/C5H12ClNO/c6-3-1-2-5(8)4-7/h5,8H,1-4,7H2

94157-97-8 Relevant articles

Preparation method of (S)-N-BOC-3-hydroxypiperidine

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Paragraph 0060; 0066; 0069; 0073; 0075; 0079, (2020/02/17)

The invention provides a preparation met...

94157-97-8 Process route

5?chloro?1,2?epoxypentane
19141-74-3

5?chloro?1,2?epoxypentane

1?amino?5?chloro?2?pentanol
94157-97-8

1?amino?5?chloro?2?pentanol

Conditions
Conditions Yield
5?chloro?1,2?epoxypentane; With ammonia; In methanol; at 60 ℃; for 10h; under 13501.4 Torr;
With sodium hydroxide; for 1h; Temperature; Pressure;
66.52%
1,5?dichloro?2?pentanol
89280-57-9

1,5?dichloro?2?pentanol

1?amino?5?chloro?2?pentanol
94157-97-8

1?amino?5?chloro?2?pentanol

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1.1: sodium hydroxide / dichloromethane / 1 h / 15 - 25 °C
2.1: ammonia / methanol / 10 h / 60 °C / 13501.4 Torr
2.2: 1 h
With ammonia; sodium hydroxide; In methanol; dichloromethane;

94157-97-8 Upstream products

  • 19141-74-3
    19141-74-3

    5?chloro?1,2?epoxypentane

  • 89280-57-9
    89280-57-9

    1,5?dichloro?2?pentanol

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