4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride
- Name 4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride
- CAS 43064-12-6
- Purity 99%
Product Details
Quality products?make an important contribution to long-term revenue and profitability. 4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride 43064-12-6 with purity >99% Low price in stock
1.What is the 4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride ?
Used in Pharmaceutical Industry:
4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride is used as a pharmaceutical intermediate for the development of drugs targeting poly(ADP-ribose) polymerase-1 (PARP-1). Its presence in benzamide analogs improves their inhibitory potential against PARP-1, making it a valuable component in the creation of therapeutic agents for treating various diseases, including cancer.
Used in Research and Development:
In the field of scientific research, 4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride serves as a key compound for studying the interactions between PARP-1 and benzamide derivatives. This research can lead to a better understanding of the enzyme's role in disease processes and the development of more effective treatments.
Used in Drug Synthesis:
4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride is utilized in the synthesis of novel drugs that aim to modulate the activity of PARP-1. Its incorporation into drug molecules can enhance their efficacy and selectivity, potentially leading to improved therapeutic outcomes for patients.
Overall, 4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride plays a crucial role in the pharmaceutical and research industries, contributing to the advancement of treatments for various diseases and the deepening of our understanding of PARP-1's biological functions.
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108-86-1,52753-63-6
bromobenzene
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79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one
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43064-12-6
1,2,3,6-tetrahydro-4-phenylpyridine hydrochloride
| Conditions | Yield |
|---|---|
|
bromobenzene;
With
iodine; magnesium;
In
tetrahydrofuran;
at 20 - 70 ℃;
for 1h;
Inert atmosphere;
N-tert-butyloxycarbonylpiperidin-4-one;
In
tetrahydrofuran;
at -50 - 20 ℃;
for 1h;
Inert atmosphere;
With
hydrogenchloride;
at 100 ℃;
for 3h;
|
71%
|
-
-
C14 H16 ClNO2
-
-
43064-12-6
1,2,3,6-tetrahydro-4-phenylpyridine hydrochloride
| Conditions | Yield |
|---|---|
|
With
methanol;
for 2.5h;
Reflux;
|
123 mg
|
2.What is the CAS number for 4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride ?
The CAS number of 4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride is 43064-12-6.
More information of 4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride 43064-12-6 are:
|
CAS?Number |
43064-12-6 |
|
Melting Point |
202-203.5 °C(lit.) |
|
Boiling Point |
267.9oC at 760 mmHg |
|
Flash Point |
119.9oC |
|
Vapor Pressure |
0.00792mmHg at 25°C |
|
HS CODE |
29333990 |
|
PSA |
12.03000 |
|
LogP |
3.19410 |
3.What are another words for 4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride ?
Synonyms?for?4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride 43064-12-6:Pyridine,1,2,3,6-tetrahydro-4-phenyl-, hydrochloride (7CI,9CI);1,2,3,6-Tetrahydro-4-phenylpyridine hydrochloride;4-Phenyl-1,2,5,6-tetrahydropyridine hydrochloride;
4.What is the molecular formula of 4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride?
The chemical formula of ?4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride is?C11H13N. HCl which containing 11 Carbon atoms,14 Hydrogen atoms and 1 Chlorine atoms,and the molecular weight of??4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride?is 195.692.
5.What is 4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride (43064-12-6) used for?
4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride is a chemical compound that features a 4-phenyl-1,2,3,6-tetrahydropyridine fragment, which is a key structural element in benzamide derivatives. This fragment enhances the inhibitory potential of benzamide analogs against poly(ADP-ribose) polymerase-1 (PARP-1), a significant enzyme involved in various cellular processes. 4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride is characterized by its light brown powder form.
Relevant articles related to 4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride:
|
Article |
Source |
|
Synthesis and SAR study of 4-arylpiperidines and 4-aryl-1,2,3,6- tetrahydropyridines as 5-HT2C agonists |
Conway, Richard J.,Valant, Celine,Christopoulos, Arthur,Robertson, Alan D.,Capuano, Ben,Crosby, Ian T. supporting information; experimental part, p. 2560 - 2564 (2012/05/05) |
6.Buy 4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride with the best price .
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