trans-Dichlorodiamineplatinum(II)
- Name trans-Dichlorodiamineplatinum(II)
- CAS 14913-33-8
- Purity 99%
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1.What is the trans-Dichlorodiamineplatinum(II) ?
ChEBI: A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a trans planar configuration around the central platinum ion. Unlike its cis-isomer, cisplatin, it does not exhibit any useful pharmacological effect and is toxic.
Trans-Dichlorodiamineplatinum(II), also known as Transplatin, is a diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a trans planar configuration around the central platinum ion. Unlike its cis-isomer, cisplatin, it does not exhibit any useful pharmacological effect and is toxic.
2.What is the CAS number for trans-Dichlorodiamineplatinum(II) ?
The CAS number of trans-Dichlorodiamineplatinum(II) is 14913-33-8.
3.What are another words for trans-Dichlorodiamineplatinum(II) ?
Synonyms?for?trans-Dichlorodiamineplatinum(II) 14913-33-8:trans-Platinumdiammine dichloride;Platinum,diamminedichloro-, trans- (8CI);NSC 131558;Transplatin;trans-DDP;trans-Diaminedichloroplatinum;trans-Diamminedichloroplatinum;trans-Diamminedichloroplatinum(II);trans-Dichlorodiamineplatinum(II);trans-Dichlorodiammine platinum;trans-Dichlorodiammineplatinum(II);trans-Platinum(II) ammonium chloride;
4.What is trans-Dichlorodiamineplatinum(II) (14913-33-8) used for?
Transplatin is the trans stereoisomer impurity of Cisplatin (C499500), an antineoplastic used in the treatment of sarcomas, some carcinomas, lymphomas, and germ cell tumors. Transplatin binds to DNA but does not exhibit the same useful pharmacological effect as its cis stereoisomer.
InChI:InChI=1/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2/rCl2H6N2Pt/c1-5(2,3)4/h3-4H3
Relevant articles related to trans-Dichlorodiamineplatinum(II):
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Conversion of Acetonitrile into Acetamide in the Co-ordination Spheres of cis- and trans-M(II)(amine)2 (M = Pt or Pd). Solution and Crystal Structural Studies |
Erxleben, Andrea,Mutikainen, Ilpo,Lippert, Bernhard , p. 3667 - 3676 (1994) |
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Characterization of the mechanism of reduction of trans-diamminetetrachloroplatinum(IV) by l-cysteine and dl-homocysteine |
Lu, Taotao,Dong, Jingran,Nan, Chunxia,Huo, Shuying,Shen, Shigang,Sun, Sufang,Shi, Tiesheng , p. 869 - 875 (2015) |
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Uracil quartet formation through non-covalent interaction with a neutral metal ammine complex |
Witkowski, Holger,Freisinger, Eva,Lippert, Bernhard , p. 1315 - 1316 (1997) |
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